Sample Collection: What impact does Mebendazole (treatment for worms) have on Microbiome Explorer test results?

Mebendazole itself does not directly interfere with assays, but the infection can affect results.
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- Nematode infections trigger mucosal responses, so testing should ideally wait 14 days post-treatment to allow biomarkers to normalise.
- If testing cannot be delayed, note Mebendazole use on the request form so clinicians can interpret results with caution.
- Limited research (mostly in children) suggests Mebendazole may increase microbiome diversity and Actinobacteria levels. sIgA levels were reduced in infected children but increased after treatment.
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https://doi.org/10.1371/journal.pntd.0005963

DOI: 10.1111/pim.12090